克利夫兰诊所招收癌症生物统计学研究博士后

  克利夫兰诊所招收癌症生物统计学研究博士后。申请者将成为Amgen统计学创新研究小组的一名研究人员。在克利夫兰诊所做博士后研究期间,要求申请者能在同行评审的期刊上发表研究成果,并能有机会在国际学术会议上展示个人的临床及数据科学研究成果。感兴趣的申请者请准备博士后申请信,博士后个人简历,研究兴趣陈述及2到3封推荐信等国外访问学者博士后申请材料。厚谱教育刚才提到的以上克利夫兰诊所博士后访问学者申请材料哪些是重中之重呢?根据厚谱教育12年的国外访问学者博士后申请经验,以上克利夫兰诊所博士后申请材料都是基本必备材料。关于克利夫兰诊所博士后申请材料的问题,您还想了解什么?厚谱教育访学顾问老师在线等大家的提问。

  Postdoctoral Fellow-Cancer BiostatisticsCleveland Clinic

  Postdoctoral Fellow – Cancer Biostatistics

  Advances in biology and immunology continue to refine our understanding of cancer pathogenesis, elucidating potential mechanisms of tumor-cell growth, survival, angiogenesis and the systematic suppression of cancer immunity progressing toward precision medicine. Implicit to the concept of precision medicine is heterogeneity of treatment benefit among patients and patient sub-populations. Yet, precision medicine presents challenges to traditional paradigms of clinical translational for which estimates of population-averaged effects are used as the basis for selecting dose-scheduling strategies as well as demonstrating comparative benefit with randomized study.

  Aspects of the traditional clinical research paradigm may not ideally suit the development of non-cytotoxics that challenge its foundational assumptions pertaining to dose-response and inter-patient exchangeability. Tumor biology and/or host immunity may better delineate target treatment populations than histology. Several emerging molecularly targeted and immunotherapeutic agents have produced durable responses in first-in-human trials. The U.S. regulatory landscape has also changed, with a growing number of accelerated approvals on the basis of single-arm trials. Collectively, these phenomena have prompted innovations with drug development strategies devised to consolidate phases in the traditional paradigm and rapidly expand accrual with “seamless” trial designs.

  This postdoctoral fellowship is devised to develop analytical and computational technology for optimal designs of trials and drug development strategies for non-cytotoxic oncology treatments that span multiple indications. With the mentorship of Dr. Brian Hobbs (Cleveland Clinic) the trainee will research techniques for effectively identifying sources of subpopulation heterogeneity from real-world databases as well as optimal designs of master protocols and seamless trials that enroll potentially non-exchangeable patients.

  The fellow will interact regularly with researchers of Amgen’s Statistical Innovation Team. Additionally, it is expected that the fellow will publish their findings in peer-reviewed academic journals as well as disseminate the ideas to both clinical and data science academic communities at conferences.

  Interested candidates should send a cover letter, CV and 2-3 reference letters to Dr Brian Hobbs at Hobbsb@ccf.org.

  Brian P. Hobbs, PhD

  Cancer Biostatistics Section Head; Associate Staff,

  Taussig Cancer Institute and Lerner Research Institute,

  Cleveland Clinic

  厚谱教育---访问学者申请领跑者,经过多年的访问学者申请服务沉淀,积累了丰富的经验和资源,如下是厚谱教育最新访问学者案例分享:

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